11-cis-Retinoic Acid-d5

Cat. No.: IBDI-437805

11-cis-Retinoic Acid-d5 is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.

Product Details

Target	RAR/RXR | PPAR | Endogenous Metabolite | Autophagy
Molecular Weight	305.47
SMILES	OC(/C=C(C)/C=C\C=C(C)\C=C\C1=C(C([2H])([2H])[2H])C([2H])([2H])CCC1(C)C)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.