11-Ketodihydrotestosterone-d3

Cat. No.: IBDI-434699

11-Ketodihydrotestosterone-d3 is the deuterium labeled 11-Ketodihydrotestosterone. 11-Ketodihydrotestosterone (11-KDHT; 5α-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11β-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells.

Product Details

Target	Androgen Receptor
Molecular Weight	307.44
Synonyms	11-KDHT-d3, 5α-Dihydro-11-keto testosterone-d3
SMILES	O[[email protected]]1(C([2H])(C[[email protected]@]([H])([[email protected]@]2(CC[[email protected]]3(CC(CC[[email protected]@]3([[email protected]]24[H])C)=O)[H])[H])[[email protected]@]1(CC4=O)C)[2H])[2H]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.