12-HETE-d8

Cat. No.: IBDI-433123

12-HETE-d8 is the deuterium labeled 12-HETE. 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway.12-HETE has both anti-thrombotic and pro-thrombotic effects. 12-HETE is a neuromodulator.

Product Details

Target	Apoptosis
Molecular Weight	328.52
SMILES	CCCCC/C([2H])=C(CC([2H])(/C([2H])=C/C([2H])=C(C/C([2H])=C(CCCC(O)=O)/[2H])/[2H])O)/[2H]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.