15-PGDH Inhibitor Screening Kit (Fluorometric)

Overview

Sample Type	Inhibitor compounds
Detection Method	Fluorescent
Assay Duration	Multiple steps standard assay
Product Type	Macrophage / Inflamm.
Platform	Microplate (12 x 8 well strips)

Target

Function	Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Tissue Specificity	Detected in colon epithelium (at protein level).
Sequence Similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Cellular Localization	Cytoplasm.

Storage & Handling

Storage	Store at +4°C.
Storage Buffer	Constituent: 100% PBS