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2',3'-cGAMP

Cat. No.: IBDI-438001

2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm.

Size (Solid):

Product Details

Target Endogenous Metabolite | STING | IFNAR
Molecular Weight 674.41
Appearance Solid
Synonyms 2'-3'-cyclic GMP-AMP
SMILES OC1([H])[[email protected]](OP(O)(OC[[email protected]](O[[email protected]@H](N2C3=NC=NC(N)=C3N=C2)[[email protected]@H]4O)([H])[[email protected]@]4([H])O5)=O)([H])[[email protected]](N6C(NC(N)=NC7=O)=C7N=C6)O[[email protected]]1([H])COP5(O)=O

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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