2,3-Dihydro-3α-methoxynimbolide

Cat. No.: IBDI-432245

2,3-Dihydro-3α-methoxynimbolide is a limonoid compound isolated from the extracts of bark, leaves, roots, and seeds of Azadirachta indica A. Juss. var. siamensis Valeton. 2,3-Dihydro-3α-methoxynimbolide exhibits potent cyto-toxicities against one or more cell lines. 2,3-Dihydro-3α-methoxynimbolide activates caspases-3, -8, and -9, while increases the ratio of Bax/Bcl-2. 2,3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in AZ521.

Product Details

Target	Apoptosis
Molecular Weight	498.56
SMILES	C[[email protected]@]12[[email protected]@](O[[email protected]@]3([H])C2=C([[email protected]@](C4=COC=C4)([H])C3)C)([H])[[email protected]@]5([H])[[email protected]]6([H])[[email protected]@]([[email protected]]1CC(OC)=O)(C(C[[email protected]]([[email protected]]6(C(O5)=O)C)OC)=O)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.