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(2S)-2'-Methoxykurarinone

Cat. No.: IBDI-430374

(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target RANKL/RANK
Molecular Weight 452.54
Appearance Solid
Synonyms 2'-O-Methylkurarinone
SMILES O=C1C[[email protected]@H](C2=CC=C(O)C=C2OC)OC3=C(C[[email protected]](C(C)=C)C/C=C(C)\C)C(O)=CC(OC)=C13
Structure Classification Flavonoids>Flavonones
Phenols>Polyphenols
Purity 98.86%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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