3-Oxo-5β-cholanoic acid

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Cat. No.: IBDI-432345

3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt (Kd=1.13 μM).

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	ROR
Molecular Weight	374.56
Appearance	Solid
Synonyms	Dehydrolithocholic acid, 3-oxoLCA
SMILES	C[[email protected]](CCC(O)=O)[[email protected]]1CC[[email protected]@]2([H])[[email protected]]3([H])CC[[email protected]]4([H])CC(CC[[email protected]]4(C)[[email protected]@]3([H])CC[[email protected]]12C)=O
Purity	99.37%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.