3,4,5-Tricaffeoylquinic acid

Cat. No.: IBDI-430900

3,4,5-Tricaffeoylquinic acid (3,4,5-triCQA) inhibits tumor necrosis factor-α-stimulated production of inflammatory mediators in keratinocytes via suppression of Akt- and NF-κB-pathways. 3,4,5-Tricaffeoylquinic acid induces cell cycle arrest at G0/G1, actin cytoskeleton organization, chromatin remodeling, neuronal differentiation, and bone morphogenetic protein signaling in human neural stem cells. 3,4,5-Tricaffeoylquinic acid has the potential for the research of aging-associated diseases.

Product Details

Target	Akt | NF-κB
Molecular Weight	678.59
Appearance	Solid
Synonyms	3,4,5-triCQA
SMILES	O=C([[email protected]]1(O)C[[email protected]@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[[email protected]@H](OC(/C=C/C3=CC=C(O)C(O)=C3)=O)[[email protected]](OC(/C=C/C4=CC=C(O)C(O)=C4)=O)C1)O
Structure Classification	Phenylpropanoids>Simple Phenylpropanols Phenols>Polyphenols
Purity	98.71%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.