5α-Hydroxy-6-keto cholesterol

Cat. No.: IBDI-432288

5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM.

Product Details

Target	Drug Metabolite
Molecular Weight	418.65
SMILES	C[[email protected]@]12[[email protected]]3([H])[[email protected]](CC([[email protected]]1(C[[email protected]](CC2)O)O)=O)([H])[[email protected]@]4([H])[[email protected]](CC3)([[email protected]@](CC4)([H])[[email protected]](C)CCCC(C)C)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.