5-NIdR

Cat. No.: IBDI-434799

5-NIdR (1-(β-D-2-Deoxyribofuranosyl)-5-nitroindole), an artificial nucleoside, exhibits the ability to inhibit the replication of DNA lesions generated by Temozolomide (HY-17364). 5-NIdR induces cancer cells apoptosis and arrests cell cycle at G0 phase. 5-NIdR enhances Temozolomide anti-tumor efficacy in murine glioblastoma model.

Product Details

Target	Apoptosis
Molecular Weight	278.26
Synonyms	1-(β-D-2-Deoxyribofuranosyl)-5-nitroindole
SMILES	O=[N+](C1=CC(C=CN2[[email protected]@H]3O[[email protected]](CO)[[email protected]@H](O)C3)=C2C=C1)[O-]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.