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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

7-Ketocholesterol

Cat. No.: IBDI-431253

7-Ketocholesterol, toxic oxysterol, inhibits the rate-limiting step in bile acid biosynthesis cholesterol 7 alpha-hydroxylase, as well as strongly inhibiting HMG-CoA reductase (the rate-limiting enzyme in cholesterol biosynthesis). 7-Ketocholesterol induces cell apoptosis.

Size (Solid):

Product Details

Target Endogenous Metabolite
Molecular Weight 400.64
Appearance Solid
SMILES C[[email protected]]1(CC2)[[email protected]](CC[[email protected]]1([H])[[email protected]](C)CCCC(C)C)([H])[[email protected]@](C(C=C3C[[email protected]]4O)=O)([H])[[email protected]@]2([H])[[email protected]]3(CC4)C
Structure Classification Terpenoids>Triterpenes
Purity 99.29%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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