8α-Tigloyloxyhirsutinolide 13-O-acetate

Cat. No.: IBDI-431190

8α-Tigloyloxyhirsutinolide 13-O-acetate is a potent and orally active STAT3 inhibitor. 8α-Tigloyloxyhirsutinolide 13-O-acetate induces early oxidative stress and pyroptosis, and late DNA damage, cell cycle arrest, apoptosis in the TNBC cells. 8α-Tigloyloxyhirsutinolide 13-O-acetate suppresses tumor cell growth in vitro and tumor growth in vivo.

Product Details

Target	STAT | Pyroptosis | Apoptosis | Reactive Oxygen Species | c-Myc | Bcl-2 Family | TrxR
Molecular Weight	420.45
SMILES	O=C(/C(C)=C/C)O[[email protected]@H](C[[email protected]]1C)C(/C(OC2=O)=C\[[email protected]](O[[email protected]]13O)(CC3)C)=C2COC(C)=O
Structure Classification	Terpenoids>Sesquiterpenes

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.