8α,9α-Epoxycoleon-U-quinone

Cat. No.: IBDI-430462

8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer effect of DOX.

Product Details

Target	P-glycoprotein
Molecular Weight	360.40
SMILES	O=C([[email protected]@]1(O[[email protected]@]213)C(C(O)=C4[[email protected]@]2(CCCC(C)4C)C)=O)C(C(C)C)=C(O)C3=O
Structure Classification	Ketones, Aldehydes, Acids

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.