A011

Cat. No.: IBDI-433516

A011 is a potent and selective ataxia-telangiectasia mutated (ATM) inhibitor with an IC50 value of 1.0 nM. A011 induces Apoptosis and cell cycle arrest at G2/M phase when combinanted with CPT-11 (HY-16562). A011 combines with CPT-11 shows antitumor activity.

Product Details

Target	ATM/ATR | Apoptosis
Molecular Weight	452.55
SMILES	CN(C)CCCOC1=NC=C(C2=CC=C(N=CC3=C4N([[email protected]](C)C5=CC=CC=C5)N=N3)C4=C2)C=C1

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.