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A1874

Cat. No.: IBDI-433358

A1874 is a nutlin-based (MDM2 ligand) and BRD4-degrading PROTAC with a DC50 of 32 nM (induce BRD4 degradation in cells). Effective in inhibiting many cancer cell lines proliferation.

Size (Solid):

Product Details

Target PROTACs | Epigenetic Reader Domain
Molecular Weight 1173.59
Appearance Solid
SMILES ClC(C=C1)=CC=C1C2=N[[email protected]](C3=NN=C(C)N3C4=C2C(C)=C(C)S4)CC(NCCOCCOCCOCCNC(C5=CC(OC)=C(NC([[email protected]]6[[email protected]](C7=C(F)C(Cl)=CC=C7)[[email protected]](C8=CC=C(Cl)C=C8F)(C#N)[[email protected]](CC(C)(C)C)N6)=O)C=C5)=O)=O
Purity 99.28%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.