AACOCF3

Cat. No.: IBDI-433125

AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease.

Product Details

Target	Phospholipase
Molecular Weight	356.47
Appearance	Liquid
Synonyms	Arachidonyl trifluoromethyl ketone
SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(C(F)(F)F)=O
Purity	≥98.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.