ABT-100

Cat. No.: IBDI-434234

ABT-100 is a potent, highly selective and orally active farnesyltransferase inhibitor. ABT-100 inhibits cell proliferation (IC50s of 2.2 nM, 3.8 nM, 5.9 nM, 6.9 nM, 9.2 nM, 70 nM and 818 nM for EJ-1, DLD-1, MDA-MB-231, HCT-116, MIAP; aCa-2, PC-3, and DU-145 cells, respectively), increases apoptosis and decreases angiogenesis. ABT-100 possesses broad-spectrum antitumor activity.

Product Details

Target	Farnesyl TransfeRase | Apoptosis
Molecular Weight	504.46
Appearance	Solid
SMILES	N#CC1=CC(C2=CC=C(OC(F)(F)F)C=C2)=C(OC[[email protected]](O)(C3=CC=C(C#N)C=C3)C4=CN=CN4C)C=C1
Purity	98.18%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.