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ACBI2

Cat. No.: IBDI-432174

ACBI2 is a highly potent and orally active VHL PROTAC (EC50: 7 nM), which selectively degrades SMARCA2 with a DC50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer.

Size (Solid):

Product Details

Target PROTACs | Epigenetic Reader Domain
Molecular Weight 1064.16
SMILES BrC1=CC=CC(N(C2=CC=C(C3CCN(CC[[email protected]@H](C)CC[[email protected]@H](C4=CC=C(C5=C(C)N=CS5)C=C4)NC([[email protected]@H]6C[[email protected]@H](O)CN6C([[email protected]](C(C)(C)C)NC(C7(CC7)F)=O)=O)=O)CC3)C=C2N8C9CCCC9)C8=N%10)=C1C%10=O

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.