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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Aclimostat

Cat. No.: IBDI-432363

Aclimostat (ZGN-1061) is a potent inhibitor of the MetAP2 enzyme and displays favorable efficacy and safety in preclinical studies. ZGN-1061 produced similar efficacy as beloranib for weight loss, improvements in metabolic parameters in a mouse model of obesity and insulin resistance, and concordant changes in gene transcription in HepG2 cells.

Size (Solid):

Product Details

Target Others
Molecular Weight 478.62
Appearance Solid
Synonyms ZGN-1061
SMILES C[[email protected]]1([[email protected]](O1)C/C=C(C)\C)[[email protected]]2([H])[[email protected]]3(CC[[email protected]]([[email protected]]2OC)OC(N4CC(C4)CCN5CCOCC5)=O)CO3
Purity ≥98.0%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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