Cat. No.: IBDP-531569
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Online InquiryTarget Information
| Sequence Similarities | Belongs to the Toll-like receptor family. Contains 19 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. |
| Cellular Localization | Cell membrane. |
| Tissue Specificity | Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells. |
| Function | May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells. |
Product Details
| Product Type | Peptide |
| Species | Human |
| Protein Length | Peptide |
| Animal free | No |
| Nature | Synthetic |
| Application | BL, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C or -80 °C. |
| Handling | Avoid freeze / thaw cycle. |