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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Aderbasib

Cat. No.: IBDI-435861

Aderbasib (INCB007839) is a potent, orally active and target specific low nanomolar hydroxamate-based inhibitor of ADAM10 and ADAM17. Aderbasib exhibits robust antineoplastic activity and can be used for cancer research, including diffuse large B-cell non-Hodgkin lymphoma, HER2 + breast cancer, gliomas, et al.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target MMP
Molecular Weight 416.47
Appearance Solid
Synonyms INCB007839, INCB7839
SMILES O=C(N(CC1)CCN1C2=CC=CC=C2)[[email protected]]([[email protected]](C3)C(NO)=O)N(CC43CC4)C(OC)=O
Purity 98.09%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.