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AFM-30a hydrochloride

Cat. No.: IBDI-435248

AFM-30a hydrochloride is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. AFM-30a hydrochloride binds to PAD2 with an EC50 value of 9.5 μM. AFM-30a hydrochloride also inhibits H3 citrullination with an EC50 value of 0.4 μM. AFM-30a hydrochloride can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.

Size (Solid):

Product Details

Target Protein Arginine Deiminase
Molecular Weight 502.97
Appearance Solid
SMILES O=C(C1=C2C(NCC2=CC=C1)=O)N[[email protected]](C3=NC4=C(N3C)C=CC=C4OC)CCCNC(CF)=N.[H]Cl
Purity 99.96%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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