AKR1C3-IN-5

Cat. No.: IBDI-432765

AKR1C3-IN-5 (Compound 6e) is a potent inhibitor of AKR1C3. AKR1C3 enzyme is overexpressed in hormone-dependent prostate and breast tumors. AKR1C3-IN-5 derived from drupanin, which exhibits half-maximal inhibitory concentration (IC50) of 9.6 ± 3 μM and selectivity index (SI) of 5.5 against MCF-7 cells.

Product Details

Target	Others
Molecular Weight	592.72
SMILES	CC(OC1=CC=C(C=C1C/C=C(C)\C)/C=C/C(N[[email protected]](C(OCC2=CC=CC=C2)=O)CCCCNC(OC(C)(C)C)=O)=O)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.