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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

AKT-IN-3

Cat. No.: IBDI-433664

AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells.

Size (Solid):

Product Details

Target Akt | Apoptosis
Molecular Weight 526.36
Appearance Solid
SMILES CNC(C[[email protected]]1NC[[email protected]@H](NC(C2=CC(C3=C(Cl)C=NN3C)=C(Cl)O2)=O)[[email protected]](C4=CC(F)=C(F)C=C4)C1)=O
Purity 99.29%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Powder: -20°C/3 years; 4°C/2 years
In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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