AMCase Polyclonal Antibody

Target Information

Target Name	AMCase
Uniprot ID	Q9BZP6
Cellular Localization	Cytoplasm and Secreted. Secretion depends on EGFR activity.
Immunogen	Synthetic peptide corresponding to Human AMCase aa 100-200 conjugated to keyhole limpet haemocyanin.
Function	Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.

Product Details

Description	Rabbit polyclonal antibody to AMCase.
Host Species	Rabbit
Clonality	Polyclonal
Purity	Immunogen affinity purified
Isotype	IgG
Conjugation	Unconjugated
Reactivity	Human
Immunogen	Synthetic peptide corresponding to Human AMCase aa 100-200 conjugated to keyhole limpet haemocyanin.
Positive Control	This antibody gave a positive signal in the following whole cell lysates: HeLa. Jurkat. THP1. HepG2. MOLT4. This antibody gave a positive result in IHC in the following FFPE tissue: Human normal lung.
Application	ICC/IF, IHC-P, WB

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Short term: 4 °C. Long term: -20 °C
Storage Buffer	pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: PBS
Handling	Avoid freeze-thaw cycles.