Anti-CTGF antibody - BSA and Azide free (Capture)

Overview

Product Type	Secreted Molecules
Host Species	Rabbit
Species Reactivity	Reacts with: Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Tissue Specificity	Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Sequence Similarities	Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain.
Cellular Localization	Secreted > extracellular space > extracellular matrix. Secreted.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.