Anti-inflammatory agent 35
Cat. No.: IBDI-431386
Anti-inflammatory agent 35 (compound 5a27) is an orally active curcumin analogue with anti-inflammatory activity. Anti-inflammatory agent 35 blocks mitogen-activated protein kinase (MAPK) signaling and p65 nuclear translocation of NF-kB. Anti-inflammatory agent 35 also inhibits yellow neutrophil infiltration and pro-inflammatory cytokine production. Anti-inflammatory agent 35 significantly attenuates lipopolysaccharide (LPS)-induced acute lung injury (ALI) in vivo.
Size (Solid):
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Product Details
| Target |
p38 MAPK | ERK | NF-κB | Interleukin Related | TNF Receptor |
| Molecular Weight |
495.52 |
| Appearance |
Solid |
| SMILES |
CC(OC1=CC=C(/C=C/C(N2C(/C(CCC2)=C/C3=CC(OC)=C(OC)C(OC)=C3)=O)=O)C=C1OC)=O |
| Purity |
99.77% |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
4°C
*In solvent : -80°C, 6 months; -20°C, 1 month |
| Handling |
Protect from light |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.
