Anti-MIP-3 beta/CCL19 antibody - BSA and Azide free (Capture)

Overview

Product Type	Chemokines
Host Species	Rabbit
Species Reactivity	Reacts with: Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
Tissue Specificity	Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
Sequence Similarities	Belongs to the intercrine beta (chemokine CC) family.
Cellular Localization	Secreted.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.