Anti-PON1 antibody - BSA and Azide free (Capture)

Overview

Product Type	Redox Metabolism
Host Species	Rabbit
Species Reactivity	Reacts with: Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Purity	Protein A purified
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Tissue Specificity	Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas.
Sequence Similarities	Belongs to the paraoxonase family.
Cellular Localization	Secreted > extracellular space.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.