Anti-Serine Palmitoyltransferase 2 antibody - BSA and Azide free (Detector)

Overview

Product Type	Redox Metabolism
Host Species	Rabbit
Species Reactivity	Reacts with: Mouse, Rat, Human
Application	Sandwich ELISA

Properties

Carrier Free	Yes
Purity	Protein A purified
Clonality	Monoclonal
Conjugate	Unconjugated
Isotype	IgG

Target

Function	Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SSSPTA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SSSPTB complex displays a preference for C18-CoA substrate.
Tissue Specificity	Widely expressed.
Sequence Similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Cellular Localization	Endoplasmic reticulum membrane.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.