Anticancer agent 58

Cat. No.: IBDI-431875

Anticancer agent 58 (compound 16) has inhibitory activity against kinds of cancer cell lines, especially in A549 and T24 with IC50s of 0.6 μM and 0.7 μM, respectively. Anticancer agent 58 induces apoptosis by activating caspase 3/8/9 activity, and induces an increase of Ca 2+ and ROS in cancer cells. Anticancer agent 58 significantly decreases mitochondrial membrane potential. Anticancer agent 58 can suppress tumor growth in T24 mouse xenograft model.

Product Details

Target	Apoptosis | Caspase | ROS Kinase
Molecular Weight	617.86
SMILES	[H][[email protected]](CC1=CC=CC=C1)(C(O[[email protected]]2CC[[email protected]]3(C(C2(C)C)CC[[email protected]@]4(C3C(C=C5[[email protected]]4(CC[[email protected]]6(CC[[email protected]](C(O)=O)(C[[email protected]@]56[H])C)C)C)=O)C)C)=O)N

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.