Anticancer agent 59

Cat. No.: IBDI-434911

Anticancer agent 59 (compound 11) has inhibitory activity against kinds of cancer cell lines, especially in A549 with IC50 of 0.2 μM. Anticancer agent 59 induces apoptosis and an increase of Ca 2+ and ROS in cancer cells. Anticancer agent 59 significantly decreases mitochondrial membrane potential. Anticancer agent 59 can suppress tumor growth in A549 mouse xenograft model.

Product Details

Target	Apoptosis | ROS Kinase
Molecular Weight	673.92
SMILES	O=C([[email protected]]1(CC[[email protected]@]2(CC[[email protected]@]3(C([[email protected]@]2(C1)[H])=CC(C4[[email protected]]5(CC[[email protected]@H](C(C)(C5CC[[email protected]]43C)C)OC(CC)=O)C)=O)C)C)C)N[[email protected]@](CC6=CC=CC=C6)(C(O)=O)[H]

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.