Anticancer agent 64

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Cat. No.: IBDI-437835

Anticancer agent 64 (compound 5m) shows cytotoxic activity in CCRF-CEM cells, with IC50 of 2.4 μM. Anticancer agent 64 shows good anticancer activity through apoptosis induction. Anticancer agent 64 induces caspase 3 and 7 activation and PARP cleavage. Anticancer agent 64 induces significant effect of mitochondria depolarization.

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Product Details

Target	Apoptosis \| Caspase \| PARP \| Bcl-2 Family
Molecular Weight	510.77
SMILES	OC([[email protected]]12[[email protected]@]([[email protected]@H](CC2)C(C)=C)([H])[[email protected]]3([H])[[email protected]@](CC1)([[email protected]]4([[email protected]]([[email protected]@]5([[email protected]@](C(C)(C6=C(SC(N)=N6)C5)C)([H])CC4)C)([H])CC3)C)C)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.