Anticancer agent 65

Cat. No.: IBDI-432382

Anticancer agent 65 (compound 4c) shows excellent activity in cancer cell lines, especially A549 cells, with an IC50 of 1.07 μM. Anticancer agent 65 induces S-phase arrest in A549 cells and increases the expression level of p53 and p21. Anticancer agent 65 causes apoptosis, ROS generation and collapse of MMP in A549 cells.

Product Details

Target	Apoptosis | MDM-2/p53 | MMP | Bcl-2 Family | Reactive Oxygen Species
Molecular Weight	589.89
SMILES	C[[email protected]]12[[email protected]]3([[email protected]@]([[email protected]@H](C[[email protected]]1([H])[[email protected]@]4([[email protected]@](C(C)([[email protected]](CC4)OC(C5CCNCC5)=O)C)([H])CC2)C)O)([H])[[email protected]@](CC3)([H])[[email protected]](C)(O)CCCC(C)(O)C)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.