Antioxidant agent-5
Cat. No.: IBDI-434248
Antioxidant agent-5 (compound D-6) is a potent antioxidant agent. Antioxidant agent-5 can inhibit oxLDL (oxidized low-density lipoprotein)-induced apoptosis and the expression of ICAM-1 and VCAM-1 in VECs. Antioxidant agent-5 suppresses oxLDL-induced increase of ROS level and nuclear translocation of NF-κB. Antioxidant agent-5 protects against oxLDL-induced endothelial injury by activating Nrf2/HO-1 anti-oxidation pathway.
Product Details
| Target |
Apoptosis | NF-κB | Keap1-Nrf2 | Reactive Oxygen Species |
| Molecular Weight |
412.49 |
| SMILES |
N#CC1=CC=C(C=C1)CN2CCN(CC2)CC3=NOC(CC4=CNC5=CC=CC=C45)=N3 |
Storage & Handling
| Shipping |
Room temperature in continental US. May vary elsewhere. |
| Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| Regulatory Status |
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. |
! For research use only, not intended for any clinical use.