Anxiolytic/nonsedative agent-1

Cat. No.: IBDI-435934

Anxiolytic/nonsedative agent-1 (compound 2b) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.

Product Details

Target	GABA Receptor
Molecular Weight	337.33
SMILES	O=C(N[[email protected]@H](C1=CC=CC=C1)C)C(C2=CNC3=C2C=C([N+]([O-])=O)C=C3)=O

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.