Aphidicolin

Cat. No.: IBDI-431059

Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.

Product Details

Target	DNA/RNA Synthesis | HSV | Apoptosis | Antibiotic | Orthopoxvirus
Molecular Weight	338.48
Appearance	Solid
SMILES	C[[email protected]@]12[[email protected]]34[[email protected]](CC[[email protected]@]1([H])[[email protected]@](C)([[email protected]](O)CC2)CO)([H])C[[email protected]]([[email protected]](CO)(O)CC4)([H])C3
Structure Classification	Terpenoids>Diterpenoids
Purity	≥99.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.