Apratoxin S4

Cat. No.: IBDI-432795

Apratoxin S4 (Apra S4) is a potent Sec61 inhibitor that prevents cotranslational translocation of secretory proteins into the endoplasmic reticulum (ER). Apratoxin S4 has antiviral effects against some flaviviruses with IC50 values ranging from 0.46 nM to 170 nM, and inhibits retinal vascular cell activation by suppressing multiple angiogenic pathways. Apratoxin S4 can be used for the research of viral infections, angiogenic diseases and cancers.

Product Details

Target	Antibiotic
Molecular Weight	828.11
Synonyms	Apra S4
SMILES	CC[[email protected]@H]([[email protected]]1C(N2CCC[[email protected]]2C(O[[email protected]@H](C[[email protected]](C[[email protected]@H]([[email protected]@H](C3=N[[email protected]](CS3)CCC(N[[email protected]](C(N([[email protected]](C(N1C)=O)C)C)=O)CC4=CC=C(C=C4)OC)=O)C)O)C)C(C)(C)C)=O)=O)C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.