ARD-266

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Cat. No.: IBDI-435094

ARD-266 is a highly potent and von Hippel-Lindau E3 ligase-based Androgen Receptor (AR) PROTAC degrader. ARD-266 effectively induces degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM.

Size (Solid):

Product Details

Target	PROTACs \| Androgen Receptor
Molecular Weight	915.51
Appearance	Solid
SMILES	O=C(C[[email protected]@H](C1=CC=CC=C1)NC([[email protected]]2N(C([[email protected]](C(C)C)C3=CC(C)=NO3)=O)C[[email protected]](O)C2)=O)N(CC4)CCC4C#CC5=CC=C(C(N[[email protected]@H]6C(C)(C)[[email protected]@H](OC7=CC=C(C#N)C(Cl)=C7)C6(C)C)=O)C=C5
Purity	99.66%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.