ARD-61

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Cat. No.: IBDI-432549

ARD-61 is a highly potent, effective and specific PROTAC androgen receptor (AR) degrader. ARD-61 potently and effectively induces AR and progesterone receptors (PR) degradation in AR+ cancer cell lines. ARD-61 induces apoptosis and effectively induces tumor growth inhibition in the MDA-MB-453 xenograft model in mice.

Size (Solid):

Product Details

Target	PROTACs \| Androgen Receptor \| Progesterone Receptor \| Apoptosis
Molecular Weight	1095.78
Appearance	Solid
SMILES	CC(C)([[email protected]](C1(C)C)NC(C2=CC=C(C=C2)C#CC3CCN(C4CCN(CC4)C(C[[email protected]@H](C5=CC=C(C6=C(C)N=CS6)C=C5)NC([[email protected]]7N(C[[email protected]@H](C7)O)C([[email protected]@H](C8=CC(C)=NO8)C(C)C)=O)=O)=O)CC3)=O)[[email protected]]1OC9=CC(Cl)=C(C=C9)C#N
Purity	99.68%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.