ASR-490

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Cat. No.: IBDI-432330

ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and Notch1/HCT116 in xenotransplanted mice.

Size (Solid):

Product Details

Target	Notch
Molecular Weight	575.69
Appearance	Solid
SMILES	C[[email protected]]([[email protected]](CC[[email protected]@]12C)([H])[[email protected]@]([[email protected]]1([H])CC[[email protected]]2([H])[[email protected]@H]([[email protected]@](OC3=O)([H])CC(C)=C3CO)C)([H])C4)(C5=O)[[email protected]@]6([[email protected]](C=C5)OC(C7=CC=CC=N7)=O)[[email protected]]4([H])O6
Purity	99.05%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.