Cat. No.: IBDA-433893
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Online InquiryTarget Information
| Target Name | ATF2 (phospho T51 + T69) |
| Uniprot ID | P15336 |
| Cellular Localization | Nucleus. |
| Immunogen | Synthetic phosphopeptide conjugated to KLH, derived from around the phosphorylation site of Threonine 69 or 51 ( D-Q-T(p)-P-T ) of Human ATF2 . |
| Function | Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex. |
Product Details
| Description | Rabbit polyclonal antibody to ATF2 (phospho T51 + T69). |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Synthetic phosphopeptide conjugated to KLH, derived from around the phosphorylation site of Threonine 69 or 51 ( D-Q-T(p)-P-T ) of Human ATF2 . |
| Positive Control | 3T3 cell extract treated with Anisomycin. HeLa cells. Human breast carcinoma tissue |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 49% PBS, 50% Glycerol, 0.88% Sodium Chloride |
| Handling | Avoid freeze-thaw cycles. |