Cat. No.: IBDA-433892
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Online InquiryTarget Information
| Target Name | ATF2 |
| Uniprot ID | P15336 |
| Cellular Localization | Nucleus. |
| Immunogen | Synthetic peptide conjugated to KLH, surrounding amino acids 60-64 (GPAR NDSVI VADQ) of Human AFT2. |
| Function | Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex. |
Product Details
| Description | Rabbit polyclonal antibody to ATF2. |
| Host Species | Rabbit |
| Clonality | Polyclonal |
| Purity | Immunogen affinity purified |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Reactivity | Mouse, Human |
| Immunogen | Synthetic peptide conjugated to KLH, surrounding amino acids 60-64 (GPAR NDSVI VADQ) of Human AFT2. |
| Positive Control | 293 and 3T3 cell extracts. Human breast carcinoma tissue. HeLa cells |
| Application | ICC/IF, IHC-P, WB |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C |
| Storage Buffer | pH: 7.40 Preservative: 0.02% Sodium Azide Constituent: 49% PBS, 0.88% Sodium Chloride, 50% Glycerol |
| Handling | Avoid freeze-thaw cycles. |