ATR-IN-14

Cat. No.: IBDI-432324

ATR-IN-14 (compound 1) is a potent ATR kinase inhibitor. ATR-IN-14 inhibits ATR signaling pathways downstream CHKI protein phosphorylation, with inhibition of 98.03% at 25 nM. ATR-IN-14 shows good anticancer activity in LoVo cells, with an IC50 of 64 nM.

Product Details

Target	ATM/ATR
Molecular Weight	393.42
SMILES	C[[email protected]@H]1COCCN1C2=NC3=C(N=CC(F)=C3C(C4=CC=NN4C)=C2)C5=CC=NN5

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.