ATR-IN-23

Cat. No.: IBDI-433679

ATR-IN-23 (Compound 34) is a potent and selective ATR inhibitor with an IC50 of 1.5 nM. ATR-IN-23 has potent antiproliferative effects on LoVo cells and synthetic lethality on HT-29 cells, and can be used in the study of DNA damage response (DDR)-deficient cancers.

Product Details

Target	ATM/ATR
Molecular Weight	458.56
SMILES	CNC1=NC2=C(N1C3=NC4=C(C(N5CCOC[[email protected]]5C)=N3)SC=C4S(C)(=O)=O)C=CC=C2

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.