Auristatin E

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Cat. No.: IBDI-432591

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin.

Size (Solid):

Product Details

Target	Microtubule/Tubulin \| ADC Cytotoxin
Molecular Weight	732.01
Appearance	Solid
SMILES	CC(C)[[email protected]](N(C)C)C(N[[email protected]](C(N([[email protected]@H]([[email protected]@H](C)CC)[[email protected]@H](CC(N1CCC[[email protected]@]1([H])[[email protected]](OC)[[email protected]@H](C)C(N[[email protected]](C)[[email protected]](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O
Purity	99.71%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years *The compound is unstable in solutions, freshly prepared is recommended.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.