Autophagy-IN-1

Cat. No.: IBDI-437483

Autophagy-IN-1 is a potent autophagy/mitophagy inhibitor, acts by selectively increasing the autophagic flux while blocking the autophagosome-lysosome fusion in cancer cells. Autophagy-IN-1 can induce apoptosis and cell cycle arrest. Autophagy-IN-1 significantly inhibits tumor growth in an HCT116 xenograft mouse model and with low toxicity. Autophagy-IN-1 can be used for researching colorectal cancer.

Product Details

Target	Autophagy | Apoptosis
Molecular Weight	427.45
SMILES	O=C1O[[email protected]@H](O/C=C([[email protected]@H]2CC3=CC=C4NC(OC(C)(C)C)=O)/C(O[[email protected]]2C3=C4)=O)C(C)=C1C

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.