Aviculin

Cat. No.: IBDI-430858

Aviculin, a lignan glycoside, is a potent anticancer agent. Aviculin reduces metabolic activity on MCF-7 cells below 50%, with an IC50 of 75.47 μM. Aviculin induces breast cancer cell apoptosis through the intrinsic apoptosis pathway. Aviculin increases expression of initiator caspase-9, executioner caspase-7, and poly (ADP-ribose) polymerase (PARP). Aviculin shows an increase in the Bax/Bcl-2 ratio.

Product Details

Target	Apoptosis | Caspase | PARP | Bcl-2 Family
Molecular Weight	506.54
SMILES	O[[email protected]]([[email protected]@H]([[email protected]]([[email protected]@H](O1)C)O)O)[[email protected]@H]1OC[[email protected]@H]2[[email protected]@H](C3=CC(OC)=C(C=C3)O)C4=CC(O)=C(OC)C=C4C[[email protected]]2CO
Structure Classification	Phenylpropanoids>Lignans

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.