AXL-IN-14

Cat. No.: IBDI-434101

AXL-IN-14 is a potent and orally active AXL inhibitor with an IC50 value of 0.8 nM. AXL-IN-14 inhibits Gas6/AXL-mediated cell migration and invasion. AXL-IN-14 decreases the expression of p-AXL and p-AKT proteins. AXL-IN-14 shows anti-tumor activity.

Product Details

Target	TAM Receptor
Molecular Weight	566.55
SMILES	FC1=CC(NC(C2=CN(C=C(C2=O)C3=CC=C(C=C3)F)C(C)C)=O)=CC=C1OC4=CC=NC5=C4OC6=CC=CC=C6N5

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.